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Chrysin is a naturally occurring isoflavone chemically extracted from the plant Passiflora coerulea. It is a natural, biologically active bioflavonoid compound extracted from many plants, honey and propolis. Chrysin has been marketed as a nutritional supplement and is especially popular among male body builders and other athletes because of its possible action in inhibiting the conversions of androgens to estrogens. It may have aromatase-inhibitory action. It may also have phytoestrogenic, antioxidant and anxiolytic activities. Chrysin's aromatase-inhibiting effects have made it popular among some body builders and athletes who use androgens.

Chrysin's ability to inhibit the aromatization of androstenedione and testosterone to estrogens has been demonstrated in the laboratory. Chrysin has been shown to be among the most potent of the natural and synthetic flavone inhibitors of human estrogen aromatase. Body builders have used it as a testosterone boosting supplement. It is also a potent antioxidant that possesses vitamin-like effects in the body. It has been shown to induce an anti-inflammatory effect. Chrysin has one other property that could add to its libido-enhancing potential. A major cause of sexual dissatisfaction among men is work-related stress and anxiety as well as "sexual performance anxiety" that prevent them from being able to achieve erections when they are expected to. It was shown to produce anti-anxiety effects comparable with diazepam, but without sedation and muscle relaxation. In other words, Chrysin produced a relaxing effect in the brain, but with no impairment of motor activity. Chrysin may therefore offer libido-enhancing effects in the aging male by increasing free testosterone; decreasing excess estrogen; and producing a safe anti-anxiety effect.

PDR Health. http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/chr_0076.shtml

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